vascularized and customized 3D-printed calcium phosphate scaffolds. Sci Rep 10:7068. https://

doi.org/10.1038/s41598-020-63742-w

Wang YI, Abaci HE, Shuler ML (2017a) Microuidic bloodbrain barrier model provides in vivo-

like barrier properties for drug permeability screening. Biotechnol Bioeng 114(1):184194.

https://doi.org/10.1002/bit.26045

Wang Y, Gunasekara DB, Reed MI, DiSalvo M, Bultman SJ, Sims CE (2017b) A microengineered

collagen scaffold for generating a polarized crypt-villus architecture of human small intestinal

epithelium. Biomaterials 128:4455. https://doi.org/10.1016/j.biomaterials.2017.03.005

Weiner AI, Jackson SR, Zhao G, Quansah KK, Farshchian JN, Neupauer KM, Littauer EQ, Paris

AJ, Liberti DC, Worthen GS, Morrisey EE (2019) Mesenchyme-free expansion and transplan-

tation of adult alveolar progenitor cells: steps toward cell-based regenerative therapies. NPJ

Regen Med 4(1):110. https://doi.org/10.1038/s41536-019-0080-9

Wilmer MJ, Ng CP, Lanz HL, Vulto P, Suter-Dick L, Masereeuw R (2016) Kidney-on-a-chip

technology for drug-induced nephrotoxicity screening. Trends Biotechnol 34(2):156170.

https://doi.org/10.1016/j.tibtech.2015.11.001

Wufuer M, Lee G, Hur W, Jeon B, Kim BJ, Choi TH, Lee S (2016) Skin-on-a-chip model

simulating inammation, edema and drug-based treatment. Sci Rep 6:37471. https://doi.org/

10.1038/srep37471

Xiang Y, Wen H, Yu Y, Li M, Fu X, Huang S (2020) Gut-on-chip: recreating human intestine

in vitro. J Tissue Eng. https://doi.org/10.1177/2041731420965318

Xu Z, Gao Y, Hao Y, Li E, Wang Y, Zhang J, Wang W, Gao Z, Wang Q (2013) Application of a

microuidic chip-based 3D co-culture to test drug sensitivity for individualized treatment of

lung cancer. Biomaterials 34(16):41094117. https://doi.org/10.1016/j.biomaterials.2013.

02.045

Yan Q, Dong H, Su J, Han J, Song B, Wei Q (2018) A review of 3D printing technology for medical

applications. Engineering 4(5):729742. https://doi.org/10.1016/j.eng.2018.07.021

Zepp JA, Morrisey EE (2019) Cellular crosstalk in the development and regeneration of the

respiratory system. Nat Rev Mol Cell Biol 20(9):551566. https://doi.org/10.1038/s41580-

019-0141-3

Zhang Q, Sito L, Mao M, He J, Zhang YS, Zhao X (2018) Current advances in skin-on-a-chip

models for drug testing. Microphysiol Syst 2:4. https://doi.org/10.21037/mps.2018.08.01

Zhang B, Gao L, Ma L, Luo Y, Yang H, Cui Z (2019) 3D bioprinting: a novel avenue for

manufacturing tissues and organs. Engineering 5(4):777794. https://doi.org/10.1016/j.eng.

2019.03.009

96

G. Aggarwal et al.